Round 1: Random Encounter

Round 2: Indominus is aware that the Skullcrawler is on his territory, Fight takes place in the Jungle Enclosure as seen in Jurassic World

VS

Just remembered that the Indominus is part cuttlefish.... someone needs to give the creator a medal.

the camoflage might come in handy. both creatures can nicely shrug off modern firepower.

but skullcrawlers are vicious, powerful and more mobile with that slithery type movement. they fought and wiped out a species of gigantic ape who are just as intelligent and powerful as indominus ever could be. plus they arent completely dwarfed by 2017 kong whos a 100ft giant. so size wise this thing might just step on indominus into the sand.

Skull crawlers only seem to be effective when in groups (at least against anything more powerful than humans) so just one skull crawler against Indominus probably won't do. Indominus went on a killing spree in Jurassic World. Killing off Anklosaurus and multiple other dinos. Killed off almost all the raptors and effortlessly took down the T Rex. I'm voting Indominus

Indominus Rex, but barely

Probably I-Rex.

Close fight but i say I-Rex, although Skullcrawler is faster

I-Rex can win.

Skullcrawler wins comfortably.

Scullcrawler.